• The effect of azithromycin for management of HIV-associated chronic lung disease on right heart function: Results from the BREATHE trial 

      Majonga, Edith D.; Mapurisa, Gugulethu Newton; Rehman, Andrea M.; McHugh, Grace; Bandason, Tsitsi; Mujuru, Hilda; Gonzalez-Martinez, Carmen; Odland, Jon O.; Kennedy, Neil; Ferrand, Rashida A. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-20)
      Background - Right heart abnormalities and pulmonary hypertension (PH) may be secondary to chronic lung disease. Chronic lung disease is common in children with HIV. In the BREATHE trial (Trial registration: NCT02426112), azithromycin (AZM) reduced the risk of acute respiratory exacerbations in children aged 6–19 years with HIV-associated chronic lung disease (HCLD) taking antiretroviral therapy. ...